Co Chair: John Krystal, Chair, Department of Psychiatry, Yale School of Medicine In addition to a wide range of scientific presentations and panels, keynote speakers included Paul Greengard, the Nobel Laureate from Rockefeller University, and Edward Scolnick, of the Staley Center at the Broad Institute, and former President of Merck Research Laboratories, and participation by video of Thomas Insel, Director of the National Institutes of Medical Health. The conference included a wide range of artistic elements, including scenes from JULY 7, 1994, by Donald Margulies; ANGELS IN AMERICA, by Tony Kushner, and PROOF, by David Auburn. In addition, William Boughton, Music Director and Principal Conductor of the New Haven Symphony, gave a fascinating lecture on composers suffering from mental illness, along with musical examples. An emotional highlight was a conversation with Rose Styron and Patrick Kennedy on William Styron’s struggle with depression, including a reading from his searing memoir, “Darkness Visible.” A specially commissioned film bringing to life global and local issues of mental illness from the Swedish filmmaker Staffan Hildebrand was shown at the event as well.
SCHEDULE OF EVENTS
Thursday May 17, 2012 – The Study at Yale, New Haven (1157 Chapel Street)
5:00 – 6:00 COCKTAIL RECEPTION
6:00 – 6:05 OPENING REMARKS
Gordon Edelstein, Artistic Director, Long Wharf Theatre
6:05 – 6:25 MENTAL ILLNESS: A NEED FOR INNOVATION
Husseini Manji, Global Therapeutic Head for Neuroscience, Johnson & Johnson
6:30 – 7:15 FINANCING INNOVATION
David Scheer (Moderator) Event Chair, President, Scheer & Company
Larry Altstiel, Vice President, Head of Neuroscience Clinical Research, Pfizer Inc.
Tony Gibney, Managing Director, Leerink Swann LLC
Jessica Chutter, Managing Director, Chairman of Biotechnology Investment Banking, Morgan Stanley
Lorence Kim, Managing Director, Goldman, Sachs & Company
Nicholas Galakatos, Managing Director, Clarus Ventures
John Puziss, Director of Technology Licensing, Yale University Office of Cooperative Research
Anne Haynes, Chief Executive Officer, Economic Development Corporation of New Haven
Jason Sibley, Vice President, GE Capital Equity
7:15 – 8:00 WILLIAM STYRON: THE MAN, THE ARTIST, THE PATIENT A Family’s Experience with Depression
Alice Flaherty, Associate Professor of Neurology & Psychiatry, Harvard Medical School
Patrick Kennedy, Co-Founder , Co-Chair, One Mind for Research
Rose Styron, Poet, Journalist & Human Right Activist
Thomas Styron, Executive Director, Community Services Network of Greater New Haven
8:30 – 9:00 REGISTRATION
9:00 – 9:30 OPENING REMARKS
David Scheer, Event Chair, President, Scheer & Company
John Krystal, Event Co-Chair, Chair, Department of Psychiatry, Yale School of Medicine
Robert Alpern, Dean, Yale School of Medicine
Gordon Edelstein, Artistic Director, Long Wharf Theatre
9:30 – 9:45 SCENE: JULY 7, 1994, by Donald Margulies
9:45 – 10:55 PHARMACEUTICAL CHALLENGE
Mikael Dolsten (Introduction) President, Worldwide Research & Development, Pfizer Inc.
Steven Paul, (Moderator) Director, Appel Institute for Alzheimer ’s Disease Research, Weill Cornell Medical College
Larry Altstiel ,Vice President, Head of Neuroscience Clinical Research, Pfizer Inc.
Jeffrey Nye, Vice President & Global Head, External Innovation for Neuroscience, Johnson & Johnson
Charles Albright, Executive Director, Neuroscience, Bristol-Myers Squibb
Marc Laruelle, Vice President & CNS Therapeutic Area Head, New Medicines, UCB Pharma, S.A.
Karin Briner, Vice President, Head of Global Discovery Chemistry, Novartis
11:00 – 11:45 TRANSFORMATIVE ADVANCES
John Krystal (Moderator) Event Co-Chair, Chair, Department of Psychiatry, Yale School of Medicine
Michael Ehlers, Senior Vice President, Chief Scientific Officer, Neuroscience, Pfizer Inc.
Evan Morris, Co-Director for Imaging, Yale PET Center
Ian Wilson, Global Head of Biology, GE Healthcare Medical Diagnostics
Franz Hefti, President & Chief Executive Officer, Acumen Pharmaceuticals
Jean-Paul Castaigne, President & Chief Executive Officer, Angiochem
Timothy Riley, Senior Vice President, Global Research, Nektar Therapeutics
11:45 – 12:00 SCENE: ANGELS IN AMERICA, by Tony Kushner
12:00 – 1:00 LUNCH
12:30 – 12:40 POETRY READING
Felicia Knaul, Director, Harvard Global Equity Initiative, Harvard University
12:40 – 1:00 WRITING “THE CENTER OF THE UNIVERSE”
Reading & comments by author Nancy Bachrach, Advisor, APCO International
1:00 – 2:15 KEYNOTE: GENETICS & GENOMIC APPROACHES TO PSYCHIATRIC DISORDERS
Richard Lifton (Introduction) Chair, Department of Genetics, Yale School of Medicine
Edward Scolnick, Chief Scientist, Stanley Center for Psychiatric Research, Broad Institute
2:15 – 3:15 2012 VANGUARD AWARD PRESENTATION
PAUL GREENGARD Vincent Astor Professor, Laboratory of Molecular & Cellular Neuroscience,
The Rockefeller University, Nobel Laureate
3:15 – 3:30 BREAK
3:30 – 3:45 SCENE: PROOF, by David Auburn
3:45 – 4:20 GENES TO PATHOPHYSIOLOGY TO TREATMENT OF NEUROPSYCHIATRIC
DISORDERS: FOCUS ON AUTISM (Intro by Matthew State)
Access to Care
Mark Friedlander, Chief Medical Officer, Aetna Behavioral Health
Gene Discovery in Autism
Matthew State, Vice Chair, Department of Psychiatry, Yale School of Medicine
Genes to An Actionable Understanding of Biology in Autism
Nenad Sestan, Associate Professor of Neurobiology, Yale School of Medicine
4:20 – 5:00 MENTAL ILLNESS AND MUSICAL CREATIVITY
Howard Feldman (Introduction) Professor, Head of Division of Neurology & Psychiatry, University of British Columbia
William Boughton, Music Director & Principal Conductor, New Haven Symphony Orchestra
5:00 – 6:35 GLOBAL CHALLENGE OF MENTAL ILLNESS
Special Keynote: Mental Illness as a New Challenge Disease
Julio Frenk, Dean of Faculty, Harvard School of Public Health
Robert Sebbag (Moderator) Director, Access to Medicines Group, Sanofi
Felicia Knaul, Director, Harvard Global Equity Initiative, Harvard University
Howard Feldman, Professor, Head of Division of Neurology & Psychiatry, University of British Columbia
Gerald Friedland, Professor of Medicine & Epidemiology, Yale School of Medicine
Alice Forrester, Executive Director, Clifford W. Beers Guidance Clinic, Inc.
6:35 – 6:45 THOMAS INSEL Director National Institute of Mental Health
Video remarks
6:45 – 7:45 COCKTAIL RECEPTION
7:45 – 9:30 DINNER
SONG: NEXT TO NORMAL: “I Miss the Mountains”, by Brian Yorkey & Tom Kitt
Performed by Broadway star Jessica Phillips
MENTAL ILLNESS – A TEN MINUTE SNAPSHOT
Staffan Hildebrand Filmmaker
PATRICK KENNEDY: CLOSING COMMENTS
Co-Founder, Co-Chair, One Mind for Research